By The Life Science Report
Source: Streetwise Reports 07/08/2020
An update on Can-Fite BioPharma’s multiple drug treatment trials is provided in a Dawson James report.
In a July 6 research note, Dawson James analyst Jason Kolbert provided an update on Can-Fite BioPharma Ltd. (CANF:NYSE.MKT).
The Israel-based firm recently raised $3.4 million in capital, which Kolbert wrote is sufficient to get it through its upcoming catalysts. He expects additional raises in the future, however and added that “investors need to balance the raises against scientific progress.”
He reported on what is new with Can-Fite’s primary drug candidates, Namodenoson and Piclidenoson.
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“Both hold great promise as alternative therapies with what appears to be a more favorable side effects profile,” commented Kolbert.
Additional Phase 2 data are available for Namodenoson in liver cancer, and they “shine,” Kolbert noted. Results showed that overall liver fat volume decreased with a high significance in patients who received Namodenoson versus those who received a placebo.
Also statistically significant was the percentage of fat volume decrease. Among the cohort that was treated with Namodenoson 12.5 milligrams (12.5 mg), the decline was 3.68%, and among the group that got 25 mg of Namodenoson, it was 4.33%. These compare to the 2.61% decrease among the placebo patients.
Next for Namodenoson is a Phase 3 pivotal trial, the design for which the U.S. Food and Drug Administration approved. Currently, the European Medicines Agency is reviewing the study protocol and registration plan.
Regarding Piclidenoson, enrollment now is about half complete for both of the Phase 3 pivotal trials, the ACROBAT study in moderate to severe rheumatoid arthritis and the COMFORT study in psoriasis.
Kolbert concluded, “Piclidenoson results in not one but two studies (ACROBAT and COMFORT) are coming, and there is even data in COVID. As a result, we would hold on, and let’s get to the data.”
Dawson James has a Buy rating and a $7 per share target price on Can-Fite BioPharma, which is now trading at about $1.83 per share.
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Disclosures for Dawson James Securities, Can-Fite BioPharma Ltd., July 6, 2020
The Firm does not make a market in the securities of the subject Company (s). The Firm has NOT engaged in investment banking
relationships with CANF in the prior twelve months, as a manager or co-manager of a public offering and has NOT received compensation resulting from those relationships. The Firm may seek compensation for investment banking services in the future from the subject Company (s). The Firm has received other compensation from the subject Company (s) in the last 12 months for services unrelated to managing or co-managing of a public offering.
Neither the research analyst(s) whose name appears on this report nor any member of his (their) household is an officer, director or advisory board member of these companies. The Firm and/or its directors and employees may own securities of the company(s) in this report and may increase or decrease holdings in the future. As of June 30, 2020, the Firm as a whole did not beneficially own 1% or more of any class of common equity securities of the subject company(s) of this report. The Firm, its officers, directors, analysts or employees may affect transactions in and have long or short positions in the securities (or options or warrants related to those securities) of the company(s) subject to this report. The Firm may affect transactions as principal or agent in those securities.
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( Companies Mentioned: CANF:NYSE.MKT,
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